The insufficiency of current therapy methods

Currently there are only two approved medications against male pattern baldness (Regaine with the active substance minoxidil and Propecia with the active substance finasteride), some therapeutic methods against alopecia areata and some unspecific drugs against androgenetic alopecia in women. But these therapies all have serious disadvantages. First of all they are not able to regrow hair significantly. Only very few hair can be regrown, except some spontaneous healing in few alopecia areata patients. The drugs have to be taken the whole life long, they are very expensive and they can have side-effects, e.g. Finasterid can lower libido and Minoxidil can affect blood pressure. About 20-40% of the minoxidil users and about 15% of the finasteride users donīt have any success at all. Additionally the drugs sometimes cause shedding phases, during which the patients loose very much hair. In some patients this additional hairloss is permanent. Women with androgenetic alopecia sometimes profit from the use of special anti-baby pills (like e.g. Diane). But these anti-baby pills also have some side-effects and there is only minimal regrowth. They have to be taken lifelong, too. Alopecia areata is usually treated by some form of topical immune therapy. Some alopecia areata patients report results by acupuncture. But a complete cure is rare. The safety and efficiency of all the other pills and lotions hasnīt been tested sufficiently in contolled clinical trials.